Department of Chemical Biology and Genetics

The main directions of research include preparation of new low-molecular organic substances that can specifically interact with key proteins of signaling and regulatory pathways in the cell; the study of their biological activity and the development of appropriate testing methods and their introduction into routine, mostly robotic screening of existing chemical libraries, substances, plant extracts, microorganisms as well as newly prepared derivatives. The identity and purity of newly prepared derivatives (especially phytohormones, plant growth regulators and biostimulants), including fluorescent or isotopically labeled substances, is tested by a set of physico-chemical methods including high resolution mass spectrometry and nuclear magnetic resonance.

Mgr. Karel Doležal, Dr., DSc.

Head of Department, Senior Researcher, Faculty of Science, Palacký University Olomouc
+420 585 634 940, karel.dolezal@upol.cz

He has since 1996 been working as a researcher in Laboratory of Growth Regulators of Faculty of Science, Palacký University Olomouc and Institute of Experimental Botany of AS CR. He studied Inorganic chemistry at Faculty of Science and Molecular biology at Faculty of Medicine, Palacký University Olomouc. His specializes in synthesis of poly-substituted purine derivatives, relation between their structure and biological activity, analytical chemistry of cytokinins and other plant hormones. He is the author or co-author of more than 140 papers in impacted journals and more than 65 granted patents. He has been involved in 9 grant projects as investigator or co-investigator in the past 10 years. He is an editor and member of editorial board of Plant Growth Regulation, South African Journal of Botany, and International Journal of Molecular Sciences.

Education:

  • 1985 – 1990 – MSc. in anorganic chemistry, Faculty of Natural Sciences, Palacky University in Olomouc
  • 1992 – 1996 – Dr. in molecular biology, Faculty of Medicine, Palacky University in Olomouc
  • 2014 – Research Professor of Biological-Ecological Sciences, Academy of Sciences of the Czech Republic

Employment:

  • 1990 – 1992 – researcher in Research Institute for Fodder Crops, Ltd. Troubsko, Research station Zubří
  • 1992 – present – researcher in Institute of Experimental Botany of the Academy of Sciences of the Czech Republic, Olomouc
  • 1996 – present – researcher in Laboratory of Growth Regulators of Faculty of Sciences Palacky University & Institute of Experimental Botany of the Academy of Sciences of the Czech Republic, Olomouc
  • 2011 – present – senior researcher, Head of Chemical Biology and Genetics Department, Centre of the Region Haná for Biotechnological and Agricultural Research

Research orientation:

  • synthesis of polysubstituted purine derivatives, relation between their structure and biological activity, analytic chemistry of cytokinins and other plant hormones – HPLC, immunoaffinity chromatography, mass spectrometry, biosynthesis and metabolism of aromatic and isoprenoid cytokinins
  • published 110 papers in international journals (WOS) (3 219 citations according to WOS, 2 852 excluding auto-citations, h-index = 28)
  • author or co-author of 50 granted patents and of 4 new patent applications

International experience:

  • 1996 – 1997 (6 m): Bayreuth University, Bayreuth, Germany, post-doc
  • 1997-1999 (12 m): Swedish Agriculture University Umeå, Umeå, Sweden, post-doc
  • several short-term study stays

Membership:

  • editor and member of Editorial Board of Plant Growth Regulation journal (Springer, IF 2 333), South African Journal of Botany (Elsevier, IF 1 244)

Grants and projects:

  • investigator or co-investigator of 9 grant projects (GAČR, NAZV, IGA AV ČR)

List of employess

Jitka FRÉBORTOVÁ

Senior researcher, Faculty of Science, Palacký University
+420 585 634 871, jitka.frebortova@upol.cz

Mgr. Pavel MAZUROVÁ, Ph.D.

Senior researcher, Faculty of Science, Palacký University
+420 585 634 899, pavel.mazura@upol.cz

Mgr. Lukáš SPÍCHAL, Ph.D.

Senior researcher, Faculty of Science, Palacký University
+420 585 634 855, lukas.spichal@upol.cz

Nuria De DIEGO, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 830, nuria.de@upol.cz

Mgr. Markéta ULBRICHTOVÁ (GEMROTOVÁ), Ph.D. 

Junior researcher, Maternity leave, Faculty of Science, Palacký University
+420 585 634 899, marketa.gemrotova@upol.cz

Mgr. Jan HUMPLÍK

Junior researcher, Faculty of Science, Palacký University
+420 585 634 945, jan.humplik@upol.cz

RNDr. Lucie JANOVSKÁ, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585632416, lucie.janovska@upol.cz

Mgr. Michal KARADY, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 858, michal.karady@upol.cz

Mgr. Pavel KLIMEŠ, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 899, pavel.klimes@upol.cz 

Ing. Radoslav KOPRNA, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 945, radoslav.koprna@upol.cz

Mgr. Václav MIK, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 785, vaclav.mik@upol.cz

Mgr. Jaroslav NISLER, Ph.D.

Researcher, Faculty of Science, Palacký University
+420 585 634 784, jaroslav.nisler@upol.cz

Mgr. Aleš PĚNČÍK, Ph.D.

Junior Researcher, Faculty of Science, Palacký University
+420 585 634 862, ales.pencik@upol.cz

Mgr. Ondřej PLÍHAL, Ph.D.

Junior Researcher, Faculty of Science, Palacký University
+420 585 634 373, ondrej.plihal@upol.cz

Mgr. Lucie PLÍHALOVÁ, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 940, lucie.plihalova@upol.cz

Mgr. Kateřina PODLEŠÁKOVÁ, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 852, katerina.podlesakova@upol.cz

Mgr. Tomáš POSPÍŠIL, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 786, tomas.pospisil@upol.cz

Mgr. Zdeněk ŠPÍŠEK, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 945, zdenek.spisek@upol.cz

RNDr. Marek ZATLOUKAL, Ph.D.

Junior researcher, Faculty of Science, Palacký University
+420 585 634 953, marek.zatloukal@upol.cz

Chao ZHANG, Ph.D.

Junior researcher, Faculty of Science, Palacký University +420 585 634 784, chao.zhang@upol.cz

Mgr. Magdaléna BRYKSOVÁ

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 783, magdalena.bryksova@upol.cz

Mgr. Noemi BUCHAROVÁ

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 896, noemi.bucharova@upol.cz

Alba Esteban HERNANDIZ, MSc.

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 852, alba.estebanhernandiz@upol.cz

Mgr. Martin HÖNIG

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 784, martin.honig@upol.cz

Mgr. Adéla HÝLOVÁ

Ph.D. student, Faculty of Science, Palacký University
+420 585 63 4852, adela.hylova@upol.cz

Mgr. Barbora PAŘÍZKOVÁ         

Ph.D. student, Faculty of Science, Palacký University
+420 585 63 4861, barbora.parizkova@upol.cz

Mgr. Michal POLÁK         

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 852, michal.polak@upol.cz

Mgr. Ivan PETŘÍK 

Ph.D. student, Faculty of Science, Palacký University
+420 585 63 4861, ivan.petrik@upol.cz 

Mgr. Pavla ŠIMUROVÁ    

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 905, pavla.simurova@upol.cz

Lydia UGENA GARCIA-CONSUEGRA MSc.

Ph.D. student, Faculty of Science, Palacký University
+420 585 634 852, lydia.ugena@upol.cz

Jarmila BALONOVÁ

Laboratory worker, Faculty of Science, Palacký University
+420 585 634 830, jarmila.balonova@upol.cz

Ing. Jana KOČÍŘOVÁ

Laboratory worker, Faculty of Science, Palacký University
+420 585 63 783, jana.kocirova@upol.cz

Ing. Tereza KUBICOVÁ SKUTKOVÁ

Secretary, Faculty of Science, Palacký University
+420 585 634 670, tereza.kubicova@upol.cz

Bc. Petr KUCZMAN

Laboratory worker, Faculty of Science, Palacký University
+420 585 634 945, petr.kuczman@upol.cz

Ing. Jan LAZECKÝ

Laboratory worker, Faculty of Science, Palacký University
+420 585 634 945, jan.lazecky@upol.cz

Iria MANEIRO

Laboratory worker, Faculty of Science, Palacký University
+420 585 634 852, iria.maneiro@upol.cz

Mgr. Jana NOSKOVÁ       

Scientific worker, Faculty of Science, Palacký University
+420 585 634 899, jana.noskova@upol.cz

Mgr. Hana OMÁMIKOVÁ

Scientific worker, Faculty of Science, Palacký University
+420 585 634 944, hana.omamikova@upol.cz

Mgr. Zuzana PĚKNÁ         

Scientific worker, Faculty of Science, Palacký University
+420 585 634 899, zuzana.pekna@upol.cz

Lien YU-CHEN, MBA

Secretary, Faculty of Science, Palacký University
+420 585 634 670, yuchen.lien@upol.cz

Ing. Hana SVOBODOVÁ

Scientific worker, Faculty of Science, Palacký University
+420 585 634 861, hana.svobodova@upol.cz

František ŠKAŘUPA

Scientific worker, Faculty of Science, Palacký University
+420 585 631 471, frantisek.skarupa@upol.cz

Mgr. Karolína WOJEWODOVÁ

Scientific worker, Faculty of Science, Palacký University
+420 725 269 606, karolina.wojewodova@upol.cz