Physical biology UP

The research group Physical biology consists of four subgroups:

Reactive oxygen species in biological systems (leader: Doc. RNDr. Pavel Pospíšil, Ph.D.)

We study the origin of radical and non-radical reactive oxygen species (ROS) inside plant and animal cells. We focus on the mechanism and the site of ROS formation, ROS scavenging by enzymatic and non-enzymatic antioxidants, and on the investigation of deleterious effects of ROS on lipids (lipid peroxidation) and proteins (protein oxidation).

Molecular and cellular pharmacology (leader: Prof. RNDr. Viktor Brabec, DrSc.)

The main research objective of our group is to increase knowledge and understanding of the mechanisms of biological (antitumor and antibiotic) action of metallodrugs and to use this enhanced knowledge to develop new classes of metallodrugs with truly novel mechanisms of action and novel spectra of biomedical activity.

Structure and function of protein complexes (leader: RNDr. Roman Kouřil, Ph.D.)

Our research is focused on the isolation and structural and functional characterization of protein complexes using single-particle (cryo) electron microscopy, electron tomography, and image analysis. We focus our attention mainly on protein supercomplexes involved in photosynthesis in a broad range of organisms, from cyanobacteria, diatoms, brown and green algae to land plants.

Biophysical aspects of plant physiology (leader: Doc. RNDr. Dušan Lazár, Ph.D.)

We study i) stress- and senescence-induced changes in plant functioning using the measurement of chlorophyll fluorescence in vivo, plant water status, leaf optical properties, and cell membrane stability, ii) electrical signals and their physiological response in the carnivorous plants and Arabidopsis thaliana and iii) various aspects of photosynthesis and its regulation by mathematical modeling.

prof. RNDr. Petr Ilík, Ph.D.

Head of group
+420 585 634 153, petr.ilik@upol.cz

Prof. RNDr. Petr Ilík, Ph.D. works as a Senior Researcher, Head of the Physical Biology Group in CRH, and as a Professor of Biophysics at Palacký University. He studied Biophysics and Chemical Physics at the Faculty of Science, Palacký University Olomouc. His research is focused on various aspects of primary photosynthetic reactions in plants and on the detection of plant stresses by modern biophysical techniques. He cooperates with commercial subjects in the development of new devices for plant stress detection. He has published more than 60 papers and has been involved in more than 25 grant projects as an investigator, co-investigator, or member of the management team.

Education:

  • 1991 – Biophysics and Chemical Physics, Faculty of Science, Palacký University in Olomouc
  • 1995 – Ph.D., RNDr. in Biophysics, Palacký University in Olomouc
  • 2003 – habilitation in Biophysics, Masaryk University in Brno
  • 2011 – professorship in Biophysics, the degree attained at the Palacký University in Olomouc

Employment:

  • 1995 – 2003 – research assistant, Faculty of Science, Palacký University in Olomouc
  • 2003 – 2011 – associate professor, Faculty of Science, Palacký University in Olomouc
  • 2011 – 2020 - professor of Biophysics, Faculty of Science, Palacký University in Olomouc
  • Since 2021 - professor of Biophysics, CRH, Czech Advanced Technology and Research Institute, Palacký University in Olomouc

Research focus:

  • biophysics of photosynthesis
  • detection of plant stresses
  • more than 60 papers published (50 entries at the Web of Science; 750 citations, h-index 21), over 50 conference presentations

International experience:

  • 2001 – 2008 – Department of Plant Physiology and Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland (7 months)
  • 2006 – Bioenergetics Laboratory, University of Geneva, Geneva, Switzerland (1 week)

Membership:

  • International Society of Photosynthesis Research
  • Czech Society for Experimental Plant Biology

Grants and projects:

  • principal investigator, co-investigator or team member in more than 25 national (Grant Agency of the Czech Republic, Ministry of Education, Youth and Sports of the Czech Republic) and international (6th Framework Programme of European Commission) projects